Hearing Status of Children and Adolescents With Familial Adenomatous Polyposis

نویسندگان

چکیده

Background/aim Chemopreventative therapeutics may be helpful in familial adenomatous polyposis (FAP) management; however, prospective chemopreventative studies are complicated by potential ototoxicity and pre-existing hearing loss. The aim of this study was to establish compare baseline status children adolescents with FAP their unaffected siblings. Patients methods Twenty pediatric patients documented mutation the coli (APC) gene nine sibling controls underwent evaluation, including audiometry, speech perception testing, middle inner ear physiologic measures. Results cohort were compared cohort. Two (5%) presented loss unknown etiology, likely unrelated diagnosis. No significant differences found any measures between groups. Conclusion Mutation APC is not necessarily indicative higher risk for population.

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ژورنال

عنوان ژورنال: Anticancer Research

سال: 2021

ISSN: ['0250-7005', '1791-7530']

DOI: https://doi.org/10.21873/anticanres.14901